SFGel Gel

Silk fibroin gel, minimum fibroin content 2%. Applications for cell encapsulation and drug delivery. Injectable format for in situ gelation.

SFGel-A Functionalized Gel

Silk fibroin gel functionalized with alkyne/azide, fibroin content >2%. Applications for cell encapsulation and drug delivery. Injectable format for in situ gelation. Stable binding between cells and drugs and gel through cross-linking.

SFGel-S Functionalized Gel

Silk fibroin gel functionalized with sulfhydryl groups, fibroin content >2%. Applications for cell encapsulation and drug delivery. Injectable format for in situ gelation. Stable binding between cells and drugs and gel through cross-linking.

SFD3S Fiber

Silk fibroin fiber made by D3SS, ⏀ <10 μm. Applications for sutures and tendon and ligament substitutes. Support fibers for fibrillar tissue scaffolds.

SFD3S-S Functionalized Fiber

Silk fibroin fiber made by D3S, functionalized with sulfhydryl groups. Applications for tissue scaffolds with specific interaction with the indicated cell lines. Axonal reconnection.

SFD3S-A Functionalized Fiber

Silk fibroin fiber made by D3S, functionalized with alkyne/azide. Applications for tissue scaffolds with specific interaction with the indicated cell lines. Axonal reconnection.

SFMesh Mesh

Silk fibroin mesh made by electrospinning, density 0.2g/cm2. Applications as a 2D cell substrate for tissue engineering.

SFMesh-S Functionalized Fesh

Silk fibroin mesh made by electrospinning functionalized with sulfhydryl groups, density 0.2g/cm2. Applications as a 2D cell substrate with specific interaction with the indicated cell lines.

SFMesh-A Functionalized Mesh

Silk fibroin mesh made by electrospinning functionalized with alkyne/azide, density 0.2g/cm2. Applications as a 2D cell substrate with specific interaction with the indicated cell lines.

FSFilm Film

Silk fibroin made by water annealing, density 0.2g/cm2. Applications as a 2D substrate in tissue engineering and in organ-on-a-chip format.

FSFilm-S Functionalized Film

Silk fibroin film manufactured by water annealing functionalized with sulfhydryl groups, density 0.2g/cm2. Applications as a 2D substrate in tissue engineering and in organ-on-a-chip format with specific interaction for indicated cell lines.

FSFilm-A Functionalized Film

Silk fibroin film manufactured by water annealing functionalized with alkyne/azide, density 0.2g/cm2. Applications as a 2D substrate in tissue engineering and in organ-on-a-chip format with specific interaction for indicated cell lines.

STub Tubular Scaffolds

Silk fibroin tubular scaffolds manufactured by D3S, internal ⏀ 0.1-2.0mm. Applications for connection with vessels of the circulatory system with controlled permeability. Applications for regeneration of nerve connections.

STub-F Functionalized Tubular Scaffolds

Silk fibroin tubular scaffolds manufactured by D3S, internal ⏀ 0.1-2.0mm, functionalized by sulfhydryl groups with peptides and/or neurotrophic factors. Applications for connection with vessels of the circulatory system with controlled permeability. Applications for regeneration of nerve connections. Specific interaction with endothelial and nervous system cells. Controlled release of growth factors.

STub-TAB Functionalized Tubular Scaffolds

Silk fibroin tubular scaffolds manufactured by D3S, internal ⏀ 0.1-2.0mm, functionalized with peptides or neurotrophic factors by alkyne/azide. Applications for connection with vessels of the circulatory system with controlled permeability. Applications for regeneration of nerve connections. Specific interaction with endothelial and nervous system cells. Controlled release of growth factors.

STub Bi-tubular Scaffolds

Silk fibroin double-tube scaffolds manufactured by D3S, internal ⏀ 0.1-2.0mm. Applications for connection with vessels of the circulatory system with controlled permeability. Applications for regeneration of nerve connections.

STub-F Functionalized Bi-tubular Scaffolds

Silk fibroin scaffolds manufactured by D3S, internal ⏀ 0.1-2.0mm, functionalized by sulfhydryl groups with peptides or different neurotrophic factors. Applications for connection with vessels of the circulatory system with controlled permeability. Applications for regeneration of nerve connections. Specific interaction with endothelial and nervous system cells. Controlled release of growth factors.

STub-TAB Functionalized Bi-tubular Scaffolds

Silk fibroin double-tube scaffolds manufactured by D3S, internal ⏀ 0.1-2.0mm, functionalized by alkyne/azide with peptides or different neurotrophic factors. Applications for connection with vessels of the circulatory system with controlled permeability. Applications for regeneration of nerve connections.

Q-click Functionalized Fibroin

Silk fibroin functionalized with click chemistry (alkyne/azide) to incorporate drugs and biomolecules and release them in a controlled manner for therapeutic applications. Applications in tissue engineering and drug release. Use as an adhesive in tissue engineering.

Functionalized Hydrogels

Silk fibroin hydrogels, functionalized with drugs and stem cell secretome for treatment of retinal diseases (e.g., AMD). Also applicable to other diseases.

D3S Fibers for Blood Vessel Formation

Fibrillar substrates functionalized with biomolecules, to create vasculature and microvasculature of arbitrary geometriesS, ⏀ <10 μm. Hybrid STub scaffolds Tubular scaffolds, functionalized/non-functionalized, integrated with Schwann cells for peripheral nerve regeneration.

Hybrid STub Bi-tubular Scaffolds

Double-tube scaffolds, functionalized or not, integrated with Schwann cells, with separate sensory and motor phenotypes, for differentiated regeneration of peripheral nerves.

Retina-On-Chip

Organ-on-Chip for the study of the development of retinal diseases and pharmacological tests.

Commercialized by Human Retina SL.

Bruch's Membranes

Silk fibroin Bruch membranes that facilitate the formation of the retinal pigment epithelium and blood vessels on their opposite sides. It also facilitates the creation of a blood-retinal barrier.

Commercialized by Human Retina SL.

SILKforBRAIN

Minimally inasive stroke therapy (silk gels + mesenchymal stem cells).